Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1982-12-22
1985-07-23
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544383, A61K 31495, C07D40102
Patent
active
045309280
ABSTRACT:
This invention involves complexes of quinoline carboxylic acid derivatives with guanidine and guanidine carbonate. The complexes have a greater solubility and dissolution rate when compared to the parent quinoline carboxylic acid derivatives and thus are more effective anti bacterials than the parent acids.
REFERENCES:
patent: 4255424 (1981-03-01), Hannah
patent: 4292317 (1981-09-01), Pesson
Stenger, et al., "Chemical Abstracts", vol. 80, 1974, col. 27258d.
Haslam, et al., "Chemical Abstracts", vol. 99, 1983, col. 99:181462q.
Haslam John L.
Pogany Stefano A.
Hollrah Glennon H.
Merck & Co. , Inc.
Monaco Mario A.
Polk Manfred
Sudol, Jr. Michael C.
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