Quinoline amino acid derivatives of carbostyril compounds

Details Quinoline amino acid derivatives of carbostyril compounds Quinoline amino acid derivatives of carbostyril compounds

1992-08-31

1994-09-06

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546157, 546158, 5142288, 5142335, 514253, 514256, 544 99, 544128, 544238, 544333, 544405, A61K 3147, C07D21522

Patent

active

RE0347221

ABSTRACT:
Disclosed are carbostyril derivatives and their salts of the formulas ##STR1## The compounds have anti-peptic ulcer effects, and are useful as a treating agent for curing peptic ulcers in the digestive system, such as ulcers in the stomach and in the duodenum. The compounds particularly have prophylaxis and curing effects for treating chronic ulcers, for example experimental acetic acid-induced ulcers and cautery ulcers, with both low toxicity and few side-effects. Also disclosed are processes for preparing the compounds and for preparing pharmaceutical compositions containing them.

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