Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1982-07-09
1984-02-21
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
424 21, 424 32, 424 33, A61K 922, A61K 924, A61K 932
Patent
active
044329652
ABSTRACT:
A sustained release oral dosage form is provided comprising a tablet core containing a pharmaceutically effective amount of quinidine. The tablet core is coated with a sustained release polymeric coating which contains about 5 to about 20 percent by weight polyethylene glycol component having a molecular weight of from about 500 to about 200, and from about 80 to 95 percent by weight polyvinylalcohol component. The polyvinylalcohol component comprises from about one to about ten parts by weight of a partially hydrolyzed polyvinylalcohol subcomponent having a degree of hydrolysis of from about 75 to about 92 percent and about one part by weight of a substantially completely hydrolyzed polyvinylalcohol subcomponent having a degree of hydrolysis in excess of 95%.
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Hsiao Charles
Keith Alec D.
Key Pharmaceuticals, Inc.
Rose Shep K.
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