Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-03-19
1995-05-30
Prescott, Arthur C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5142295, 5142305, 514247, 514258, 514269, 514826, 514893, 544242, 544245, 544253, 544283, 544295, 544298, 544299, 544300, 544301, 544302, 544304, 544305, 544309, 544310, 544311, 548100, 548124, 548146, 548181, 548182, 548184, 548190, A61K 3141, A01N 4364, C07D41300, C07D41314
Patent
active
054201330
ABSTRACT:
Phenoxyphenylacetic acids and derivatives of general structural formula I ##STR1## have endothelin antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, inflammatory diseases, Raynaud's disease, and endotoxic shock, and asthma.
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Dhanoa Daljit S.
Fitch Kenneth J.
Veber Daniel F.
Walsh Thomas F.
Williams, Jr. David L.
Camara Valerie J.
Daniel Mark R.
DiPrima Joseph F.
Merck & Co. , Inc.
Prescott Arthur C.
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