Quinazolinone and benzoxazinone derivatives and uses thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S286000, C514S252170, C514S212020, C514S217050, C540S543000, C540S553000, C540S599000

Reexamination Certificate

active

11035506

ABSTRACT:
Compounds of the formula I:and pharmaceutically acceptable salts thereof, wherein X is CH or N, Y is C or S, Z is —(CRaRb)r— or —SO2—, A is —NR3— or —O—, R2is optionally substituted aryl or optionally substituted heteroaryl, n is 1 or 2, m is 1 when Y is C and m is 2 when Y is S, and p, q, r, R1, R3, R4, R5, R6, R7, R8, R9, R10, Raand Rbare as defined herein. The compounds are useful in the treatment of 5-HT6and 5-HT2Amediated diseases.

REFERENCES:
patent: 3819625 (1974-06-01), Ott
patent: 4387223 (1983-06-01), Yamamoto et al.
patent: 2003/0078255 (2003-04-01), Pinto
patent: WO 98/18781 (1998-05-01), None
patent: WO 98/42688 (1998-10-01), None
patent: WO 99/21840 (1999-05-01), None
patent: WO 99/37643 (1999-07-01), None
patent: WO 01/37837 (2001-05-01), None
patent: WO 01/44228 (2001-06-01), None
Russell MG and Dias R. (Curr. Top. Med. Chem, Jun. 2002; 2(6):643-54).

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