Quinazoline substituted aminomethyl benzene derivatives

Details Quinazoline substituted aminomethyl benzene derivatives Quinazoline substituted aminomethyl benzene derivatives

1987-05-18

1990-05-08

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514260, 544283, 544116, C07D23972, C07D23984, A61K 31505

Patent

active

049238736

ABSTRACT:
The present invention relates to new compounds of the formula ##STR1## where X is ##STR2## alkylene, or --S-- where R.sub.1 is hydrogen, alkyl, or aryl; W is hydrogen, hydroxy, amino, alkyloxy, aryloxy, O-alkyl, or O-aralkyl; (Y).sub.A) is --CH.sub.2 NR.sub.2 R.sub.3 where R.sub.2 and R.sub.3 may be hydrogen, substituted alkyls, aryls, or together with N form a 5 to 7 membered heterocyclic group; and Ar is a substituted or unsubstituted aryl. These compounds are useful in the treatment of various cardiac arrhythmias.

REFERENCES:
patent: 3240781 (1966-03-01), Turner et al.
patent: 4466965 (1984-12-01), Stout et al.
patent: 4562201 (1985-12-01), Stout et al.
Sun et al., ACTA Pharmaceutica Sinica, vol. 16, No. 8, Aug. 24, 1981, pp. 564-570.
Stout et al., J. Med. Chem., 27 (1984), pp. 1347-1350.

Affiliated with

Also associated with

Rating

Quinazoline substituted aminomethyl benzene derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Quinazoline substituted aminomethyl benzene derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Quinazoline substituted aminomethyl benzene derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2349381