Quinazoline derivatives for inhibiting cancer cell growth...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S266200, C514S266400, C544S235000

Reexamination Certificate

active

08003658

ABSTRACT:
The present invention relates to a novel quinazoline derivative and a pharmaceutically acceptable salt thereof for inhibiting the growth of cancer cells, a method for the preparation thereof and a pharmaceutical composition comprising same as an active ingredient.

REFERENCES:
patent: 2002/0082270 (2002-06-01), Himmelsbach et al.
patent: 602851 (1994-06-01), None
patent: WO 97/30034 (1997-08-01), None
patent: WO 99/09016 (1999-02-01), None
patent: WO 01/85760 (2001-11-01), None
patent: WO 02/068396 (2002-09-01), None
Cha et al. Journal of Medicinal Chemistry, 2009, 52, 6880-6888.
Cancer definition:, http://www.medterms.com/script/main/art.asp?articlekey=2580, accessed Nov. 27, 2007.
Albuschat, R., et al., “4-Anilinoquinazolines with Lavendustin A subunit as inhibitors of epidermal growth factor receptor tyrosine kinase: syntheses, chemical and pharmacological properties,” European J. of Medicinal Chemistry, 2004, 39, pp. 1001-1011.

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