Quinazoline derivatives

Details Quinazoline derivatives Quinazoline derivatives

2006-09-12

2006-09-12

McKenzie, Thomas C. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C544S287000, C544S293000, C544S244000, C514S266200, C514S266210, C514S266220, C514S266230, C514S266240, C514S266300, C514S266400

Reexamination Certificate

active

07105669

ABSTRACT:
A compound of formula (I) or a salt, ester or amide thereof; where X is O, or S, S(O) or S(O)2or NR10where R10is hydrogen or C1-6alkyl, and R1, R2, R3, R4, R5, R6, R7, R8and R9are various specified organic groups. These compounds are inhibitors of aurora 2 kinase, and are useful in the treatment of cancer.

REFERENCES:
patent: WO 96/30347 (1996-10-01), None
patent: WO 98/47541 (1998-10-01), None
patent: 2004/013091 (2004-02-01), None
PCT/GB00/03562 International Search Report.

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