Quinazoline derivative

Details Quinazoline derivative Quinazoline derivative

2011-06-14

2011-06-14

Ward, Paul V. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S262100, C514S265100, C544S253000, C544S254000, C544S256000, C544S257000, C544S262000, C544S264000

Reexamination Certificate

active

07960394

ABSTRACT:
This invention provides a compound or its pharmaceutically-acceptable salt of formula (I)wherein R1represents a lower alkyl group et al; R2and R3are same and different and represents hydrogen atm et al; R4represents the substituent of the formula (II) et al;X1represents NH, O or S; Y represents N or C; Ar is a divalent substituent derived from aryl et al, by removing two hydrogen atoms therefrom; the ring A represents a 5- or 6-membered heteroaryl group; this compounds has a histamine-H3 receptor antagonistic effect or a histamine-H3 receptor inverse-agonistic effect and is useful for preventive or remedy of metabolic system diseases, circulatory system diseases or nervous system diseases.

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patent: WO 03/042359 (2002-11-01), None

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