Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid
Patent
1975-08-15
1977-07-05
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Organic pressurized fluid
424 46, 42424854, 424250, 260246B, 260268BQ, C07D41314, A61K 3147
Patent
active
040340759
ABSTRACT:
Compounds of the general formula (I): ##STR1## in which R.sub.1, R.sub.2 and R.sub.3 may be the same or different and each represents a hydrogen atom, an alkyl group, a nitro group, a halogen atom or a group of the formula --NR.sub.4 R.sub.5 or --OR.sub.4 ; in which the groups R.sub.4 and R.sub.5 may be the same or different and each represent a hydrogen atom, or an alkyl, alkenyl or cycloalkyl group (which alkyl group may optionally be substituted by alkoxy, hydroxy, amino, alkylamino, dialkylamino or aryl groups) or R.sub.4 and R.sub.5 together with the nitrogen atom form a heterocyclic ring which may optionally contain additional hetero atoms, e.g. morpholino or piperazinyl; and R.sub.6 represents a hydrogen atom or an alkyl group.
These compounds have biological activity, particularly in inhibiting the release of spasmogenic substances arising as a consequence of antigen-antibody reactions.
REFERENCES:
giannini, "Chem. Abstracts" vol. 75 (1971), No. 20222a.
Bays et al., "Chem. Abstracts" vol. 80 (1974), No. 146174h.
Bays David Edmund
Ellis Gwynn Pennant
Peel Mervyn Evan
Waters David Martin
Allen & Hanburys Limited
Jiles Henry R.
Ramsuer R. W.
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