Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1995-06-02
1996-11-26
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424488, 424489, A61K 916, A61K 950
Patent
active
055783228
ABSTRACT:
A coated preparation prepared by coating drug particles having a disagreeable taste with a mixture comprising a hydrophobic substance with a melting point of 45.degree. to 90.degree. C. and a surfactant with a lower melting point and heat treating the coating layer at a temperature ranging from around the melting point of the surfactant up to the melting point of the hydrophobic substance to modify the nature of the coating layer. This preparation can release the drug quickly which sufficiently suppressing the disagreeable taste.
REFERENCES:
patent: 4080445 (1978-03-01), Lin
patent: 5000965 (1991-03-01), Killeem
patent: 5057319 (1991-10-01), Gottwald
patent: 5260074 (1993-11-01), Sipos
JP61238336 Fushiya Yoshihiko Preparation of Coated Material Having Gradual Release Property Oct. 23, 1986.
Shiozawa Hiroyoshi
Sugao Hiroya
Yamazaki Shigeru
Yano Katsuhiko
Benston, Jr. William E.
Page Thurman K.
Yamanouchi Pharmaceutical Co. Ltd.
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