Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Reexamination Certificate
2006-07-11
2006-07-11
Sheikh, Humera N. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
C424S465000, C424S474000, C424S489000, C424S490000
Reexamination Certificate
active
07074428
ABSTRACT:
The present invention pertains to a quick disintegrating tablet in buccal cavity, characterized in that drug-containing particles with a mean particle diameter of approximately 50 to approximately 250 μm and an apparent specific gravity of approximately 0.5 to approximately 1.2 consisting of a bitter tasting drug and/or drug of inferior fluidity and a pharmaceutical preparation carrier and obtained by spray drying are added to a quick disintegrating tablet in buccal cavity comprising a drug and a saccharide. Moreover, the present invention pertains to a method for manufacturing drug-containing particles having a specific mean particle diameter and specific apparent gravity by dissolving and suspending a bitter tasting drug and/or drug of inferior fluidity and a pharmaceutical preparation carrier to a high concentration in terms of solid concentration in a solvent and spray drying this liquid and a method for manufacturing a quick disintegrating tablet in buccal cavity comprising the particles.
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Kajiyama Atushi
Kawai Hitoshi
Mizumoto Takao
Takahashi Tatsuya
Tamura Tetsuya
Astellas Pharma Inc.
Sheikh Humera N.
Townsend and Townsend / and Crew LLP
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