Quick-acting diuretic compositions

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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Details

424251, 424253, 424303, 424321, A61K 31505, A61K 3152, A61K 31625

Patent

active

043351190

ABSTRACT:
A diuretically active pharmacological composition which comprises 4-chloro-N-furfuryl-5-sulfamoylanthranilic acid (furosemide) together with at least one compound of formula (I) ##STR1## wherein R is a hydrophilic radical, capable of increasing the water solubility of the resulting compound together with a suitable pharmacological carrier.

REFERENCES:
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Albiez, Naunyn-Schmiedeberg's, Arch. of Pharm., Supplement 1 to vol. 297, 1977, Deutsche Pharm. Gesell. Abstracts R36, Ab. No. 142.
Hropot, supra, R37, Ab. No. 148
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Leilich, Arzneim,-Forsch./Drug Res., vol. 30, 1980, pp. 949-953.
Testa, Drug Metab., Marcel Dekker Inc., N.Y., pp. 265-267.
Joubert, Canad. Med. Ass. J., vol. 99, Jul. 13, 1968, pp. 57-63.
Kirk-Othmer, Enc. of Chem. Tech., John Wiley, N.Y., 3rd Ed., vol. 8, p. 17.

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