Quetiapine hemifumarate purification by crystallization

Details Quetiapine hemifumarate purification by crystallization Quetiapine hemifumarate purification by crystallization

2006-10-26

2011-10-25

Coleman, Brenda (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C540S551000

Reexamination Certificate

active

08044039

ABSTRACT:
The present invention relates to a process for preparing and purifying crystalline quetiapine hemifumarate, which comprises preparing crystalline quetiapine hemifumarate via a crystalline salt, which is not a salt of fumaric acid.

REFERENCES:
patent: 2006/0063927 (2006-03-01), Etlin et al.
patent: 0 282 236 (1988-09-01), None
patent: WO-99/06381 (1999-02-01), None
Ravikumar K. et al: “Quetiapine hemifumarate”, Acta Crystallographica, Section E: Structure Reports Online, XX, XX, vol. E61, No. 10, Sep. 14, 2005, pp. 3245-3248.

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