Quaternized phthalocyanin derivatives

Details Quaternized phthalocyanin derivatives Quaternized phthalocyanin derivatives

1983-11-14

1986-01-21

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

2602422, 2602451, 26024573, 26024574, 26024576, 2602458, 436 63, C09B 4704, C09B 4730, C09B 4732

Patent

active

045656886

ABSTRACT:
New phthalocyanin derivatives which can be used to differentiate basophils from other blood cells are disclosed. The compounds to which the present invention are quaternary salts of a substituted phthalocyanin structure wherein the substitutions are each independently hydrogen, sulfonate, or a C.sub.1 -C.sub.7 hydrocarbon, optionally containing at least one heteroatom, with the proviso that at least one of them is ##STR1## in which R.sub.1 -R.sub.3 are each independently lower alkyls, cycloalkyls or olefins of which at least one is C.sub.2 -C.sub.4 and two may join to form a ring; R.sub.4 is hydrogen or a C.sub.1 -C.sub.3 alkyl; n is an integer from 1 to 6; M is a polyvalent metal ion. It is preferred that at least two and especially at least three substitutions have the structure so set forth.

REFERENCES:
patent: 3210345 (1965-10-01), Gamlen et al.
patent: 3954392 (1976-05-01), Dien
Scott, J. Microscopy, vol. 119, (1979), pp. 373-381.

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