Quaternized nitrogen containing compounds

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424 45, 424 54, 424 59, 424 71, 424 73, 424DIG4, 424 78, 514847, 514881, 514183, 514212, 514315, 514327, 514424, 540451, 540531, 546221, 546243, 548550, A61K 709

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048370134

ABSTRACT:
The invention relates primarily to quaternized compounds having the formula ##STR1## wherein m is an integer having a value of from 1 to 4; R is alkylene having from 3 to 8 carbon atoms and is optionally substituted with C.sub.1 to C.sub.4 alkyl; R.sub.4 is alkylene having from 1 to 4 carbon atoms, phenyl or naphthyl optionally substituted with lower alkyl; Y is ##STR2## wherein R.sub.6 is hydrogen or lower alkyl; R.sub.7 is alkyl of from 1 to 30 carbon atoms; R.sub.2 and R.sub.3 are each independently selected from the group of --R.sub.4 --Y--R.sub.7 alkyl, alkyleneoxyalkyl, alkylhydroxy, aryl, aralkyl, aralkenyl, alkaryl, and alkyleneamidoalkyl radicals, said groups each having from 1 to 30 carbon atoms and at least one of R.sub.7, R.sub.2 and R.sub.3 having at least 8 carbon atoms and X.sup.-- is a chloride, bromide or iodide anion. The invention also relates to the preparation and use of said quaternized compounds.

REFERENCES:
patent: 2945863 (1960-07-01), Buc et al.
patent: 4590249 (1986-05-01), Cabestany et al.
patent: 4612188 (1986-09-01), Zorayan et al.
patent: 4645663 (1987-02-01), Grollier et al.
patent: 4732990 (1988-03-01), Login et al.
Noller, "Chemistry of Organic Compounds", 3rd Ed., 1965, p. 253.

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