Quaternary salts of dibenzo[1,4]diazepinones, pyrido-[1,4]benzod

Details Quaternary salts of dibenzo[1,4]diazepinones, pyrido-[1,4]benzod Quaternary salts of dibenzo[1,4]diazepinones, pyrido-[1,4]benzod

1984-05-09

1986-06-10

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239BD, 260239DD, 2602393T, 2602433, 2602444, 2602457, 514220, C07D40104, C07D40106, A61K 3133

Patent

active

045941904

ABSTRACT:
Quaternary salts of 11-acyl derivatives of 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, 6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one and 5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one are described.
Said quaternary salts are endowed with antiulcer, antisecretory, spasmolytic and antimuscarinic activity.

REFERENCES:
patent: 4556653 (1985-12-01), Giani et al.
Monro et al, J. Med. Chem., 6, 255, 1963.
Thomae, Chem. Abst., 90-137875s (1979).
Schmidt et al, Chem. Abst., 73-77292m (1970).
Burger, Medicinal Chem., 2nd Edition, 1960, pp. 480-481.

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