Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-06-02
1993-04-27
Ivy, C. Warren
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546292, 546303, 546338, C07D21380
Patent
active
052063712
ABSTRACT:
Quaternary pyridinium compounds, their use in inhibiting acetylcholinesterase, their roles in the prophylaxis and treatment of organophosphate poisoning, their roles in anticholinesterase therapy and their roles as agents mimicking or opposing the actions of the natural neurotransmitter acetylcholine.
REFERENCES:
Hagedorn et al. Arzneim-Forsch. (Drug Res.) 26(7) 1976, pp. 1273-1275, "Preparation and Quaternation of Pyridinealdoxime alkyl ethers".
Blanch et al. J. Chem. Soc. 1965, pp. 3734-3738, "Stability of N-Heterocyclic Oxime Derivatives".
Kao et al., J. Heterocyclic Chem., 28, 1991, pp. 1315-1324, "3-Substituted 2-Pyridinecarbaldoximes".
Markovac et al. J. Heterocyclic Chem., 14, 1977, pp. 19-26, "Synthesis of Oximes".
Glinski Jan
Hernandez Maria A.
May Sheldon W.
Powers James C.
Thornton Steve
Georgia Tech Research Corporation
Ivy C. Warren
Spivak P. G.
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