Quaternary nitrogen-containing vitamin E derivatives and uses th

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514844, 514847, 549408, 427 70, 252308, A61K 31355, C07D31172

Patent

active

053526961

ABSTRACT:
A quaternary nitrogen-containing vitamin E and quaternary nitrogen-containing polyethoxylated vitamin E are disclosed. Methods for preparing the quaternary nitrogen-containing vitamin E derivatives which comprises reacting vitamin E or polyethoxylated vitamin E with a quaternizing agent selected from quaternary halohydrins and epoxides to effect a quaternization are also disclosed. The quaternary nitrogen-containing vitamin E derivatives show an improved substantivity to skin or hair and a good water dispersibility as well as may be employed as an useful surface active agent in cosmetics.

REFERENCES:
patent: 2995513 (1961-08-01), Paschall et al.
patent: 3532751 (1970-10-01), Langher et al.
patent: 4632984 (1986-12-01), Matsunaga et al.
patent: 4663159 (1987-05-01), Brode, II et al.

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