Quaternary ammonium salts of polysaccharides, prossessing hypoch

Details Quaternary ammonium salts of polysaccharides, prossessing hypoch Quaternary ammonium salts of polysaccharides, prossessing hypoch

1988-05-02

1991-01-15

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 55, 514 57, 514 60, 536 20, 536 45, 536 52, 536 54, 536 50, 536 551, 536114, A61K 31715, A61K 3172, A61K 3173

Patent

active

049854100

ABSTRACT:
Quaternary ammonium salts of polysaccharides possessing hypochlolesterolemic activity and having the following general formula: ##STR1## in which A represents the monomer unit of a natural polysaccharide, m is a whole number between 100 and 1000, n is a whole number between 0 and 4, B is O or S or NH or NR, R is a linear alkyl radical of 1-4 carbon atoms, and X.sup.(-) is an anion such as Cl.sup.-, Br.sup.-, I.sup.-, HSO.sub.4.sup.-, CH.sub.3 O--SO.sub.3.sup.-.
Said salts are prepared by reacting a pretreated natural polysaccharide with a a quaternary ammonium salt functionalized at one of its ends with an epoxy group.

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