Quaternary ammonium salts of aromatic amine compounds, their pre

Details Quaternary ammonium salts of aromatic amine compounds, their pre Quaternary ammonium salts of aromatic amine compounds, their pre

1995-06-07

1998-06-30

Chang, Ceila

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546233, 546235, C07D21132

Patent

active

057736200

ABSTRACT:
Amine compounds of the formula (Ia): ##STR1## where m, Ar', N, T and Z are defined herein and J is a group ##STR2## are useful as precursors in the production of quaternary amines and for the treatment of pathological phenomena involving the neurokin system.

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patent: 5317020 (1994-05-01), Emonds-Alt
patent: 5340822 (1994-08-01), Emonds Alt
"Synthesis and Local Anesthetic Activity of N-Diethylaminoacetly Derivatives of Napthlyalkylamines", J. Medical Chem. 14(9):896-897 (1970).
"Central Nervous System Activity of Ethyl 1-Naphthylalkylcarbamates", J. Medicinal Chem. 13(4):747-748 (1970).
"Effects on the Isolated Human Bronchus of 48968, a Potent and Selective Nonpeptide Antagonist of the Neurokinin A (NK.sub.2) Receptors", Chem. Abstracts 118:32786. (1992).
Burger, "Medicinal Chemistry", Interscience Publisher, p. 42 (1960).

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