Organic compounds -- part of the class 532-570 series – Organic compounds – Halogen containing
Patent
1991-07-12
1992-07-21
Lone, Werren B.
Organic compounds -- part of the class 532-570 series
Organic compounds
Halogen containing
554150, 558460, 560174, 564204, 564409, 568316, 568409, 568437, 568460, 570101, 570190, 570206, 570216, C07C 1700, C07C 1702, C07C 6960, C07C 300
Patent
active
051324750
ABSTRACT:
A process is disclosed for chlorinating, brominating and/or iodinating an organic substrate containing both a single acidic hydrogen atom and at least one electron withdrawing group attached to the same carbon atom. The process replaces the single acidic hydrogen with chlorine, bromine and/or iodine and involves reacting the substrate in solution with a halogenating agent (e.g., a perhalomethane wherein the halogen substituents are I, Br and/or Cl, a trihaloacetic acid ester wherein the halogen substituents are Br and/or Cl, or a perfluoroalkyl halide wherein the halide is I, Br and/or Cl) in the presence of a quaternary ammonium fluoride catalyst of the formula R.sup.1 R.sup.2 R.sup.3 R.sup.4 NF where R.sup.1, R.sup.2, and R.sup.3 and R.sup.4 are independently chosen from the group consisting of hydrocarbyl radicals containing from 1 to about 20 carbon atoms.
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E. I. Du Pont de Nemours and Company
Lone Werren B.
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