Quaternary ammonium compounds useful as antifibrillatory agent

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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A61K 3114

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active

040014339

ABSTRACT:
Compounds containing the N-m-methoxybenzyl-N,N-dimethyl-N-2-hydroxyethylammonium cation and non-toxic salts of the N-m-methoxybenzyl-N,N-dimethyl-N-ethylammonium cation.
The compounds have antiarrhythmic properties, and are useful specifically as antifibrillatory agents.

REFERENCES:
Jones et al., Chem. Abst. vol. 58 (1963) 464e.
Saijo, Studies on Antihistamine Agents vol. 72, pp. 1444-1447.
Dvornik et al., Biochemical Pharmacology, 1963, vol. 12, pp. 229-240, Pergamon Press Ltd., Great Britain.

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