Quaternary ammonium compounds

Details Quaternary ammonium compounds Quaternary ammonium compounds

2006-03-07

2006-03-07

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

C436S811000, C514S184000, C540S465000

Reexamination Certificate

active

07008613

ABSTRACT:
A compound of formula corresponding to either formula (Ia) or (Ib):wherein:M represents a molecule that can be used for the treatment or diagnosis of pathologies caused by attack on the cartilage,R1, R2and R3represent alkyl,or R1, R2and R3together with the nitrogen atom carrying them, form a heterocycle,X represents a (C1–C6)alkylene chain in which one or more —CH2— groups are optionally replaced by sulphur, oxygen, or —NR—, —CO—, —CO—NH—, —CO2—, —SO— or —SO2—,n represents 0 or 1,Hal represents halogen,or,R4represents alkyl,Hal represents halogen,represents a molecule that can be used for the treatment or diagnosis of pathologies caused by attack on the cartilage, wherein the nitrogen atom may optionally be included in a saturated or unsaturated nitrogen-containing heterocyclic system, or included in a double bond.

REFERENCES:
Reymond et al. (Helvicta Chimica Acta—vol. 79 (1996), 1651-1669).

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