Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1994-10-12
1998-12-08
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 79, 435 792, 435363, 435 721, 436 63, 436 64, 436813, G01N 3353, G01N 33574
Patent
active
058467491
ABSTRACT:
Cellular components are quantitated using stained cell samples, computerized image analysis, and cellular standards, where the computerized image analysis value can be translated into the amount of the component per cell. The methodology is demonstrated with breast cancer cells and quantitation of the HER-2
eu gene. The quantitation is shown to have prognostic capability as to the future course of the disease.
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Czerniak et al., The Journal of Histochemistry and Cytochemistry, vol. 38, No. 4, pp. 463-466, 1990.
M.F. Press, et al., "Her-2
eu Expression in Node-negative Breast Cancer: Direct Tissue Quantiation by Computerized Image Analysis and Association of Overexpression with Increased Risk of Recurrent Disease," Cancer Research 53, 4960-4907, Oct. 15, 1993.
Press Michael F.
Slamon Dennis J.
Kresnak Mark T.
Scheiner Toni R.
The Regents of the University of California
Trecartin Richard F.
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