Radiant energy – Ionic separation or analysis – Ion beam pulsing means with detector synchronizing means
Reexamination Certificate
2011-04-26
2011-04-26
Kim, Robert (Department: 2881)
Radiant energy
Ionic separation or analysis
Ion beam pulsing means with detector synchronizing means
C250S281000, C250S282000, C250S283000, C250S286000, C250S288000, C250S3960ML, C250S3960ML
Reexamination Certificate
active
07932491
ABSTRACT:
A mass spectrometer includes a pulsed ion source that generates an ion beam comprising a plurality of ions. A first timed ion selector passes a first group of ions. A first ion mirror generates a reflected ion beam comprising the first group of ions that at least partially compensates for an initial kinetic energy distribution of the first group of ions. A second timed ion selector passes a second group of ions. A second ion mirror generates a reflected ion beam comprising the second group of ions that at least partially compensates for an initial kinetic energy distribution of the second group of ions. A timed ion deflector deflects the second group of ions to a detector assembly comprising at least two ion detectors which detects the deflected ion beam.
REFERENCES:
patent: 5144127 (1992-09-01), Williams et al.
patent: 5160840 (1992-11-01), Vestal
patent: 5166518 (1992-11-01), Freedman
patent: 5625184 (1997-04-01), Vestal et al.
patent: 5627369 (1997-05-01), Vestal et al.
patent: 5847385 (1998-12-01), Dresch
patent: 6057543 (2000-05-01), Vestal et al.
patent: 7223966 (2007-05-01), Weiss et al.
patent: 2003/0141447 (2003-07-01), Verentchikov et al.
patent: 2005/0269505 (2005-12-01), Ermer
patent: 2005/0279933 (2005-12-01), Appelhans et al.
patent: 2008/0272290 (2008-11-01), Vestal
patent: 2008/0272293 (2008-11-01), Vestal
“Notification Concerning Transmittal Of International Preliminary Report On Patentability (Chapter I Of The Patent Cooperation Treaty)” For PCT/US2009/045108, Dec. 9, 2010, 9 pages, The International Bureau Of WIPO, Geneva, Switzerland.
“Notification Of Transmittal Of The International Search Report And The Written Opinion Of The International Searching Authority, Or The Declaration” For PCT/US2010/022122, Aug. 16, 2010, 9 pages, International Searching Authority, Korean Intellectual Property Office, Seo-gu, Daejeon, Republic of Korea.
Beavis, Ronald C., et al., Factors Affecting The Ultraviolet Laser Desorption Of Properties, Rapid Communications In Mass Spectrometry, 1989, pp. 233-237, vol. 3, No. 9, Heyden & Son Limited.
Bergmann, T., et al., High-Resolution Time-Of-Flight Mass Spectrometer, Rev. Sci. Instrum., Apr. 1989, pp. 792-793, vol. 60, No. 4, American Institute Of Physics.
Beussman, Douglas J., et al., Tandem Reflectron Time-Of-Flight Mass Spectrometer Utilizing Photodissociation, Analytical Chemistry, Nov. 1, 1995, pp. 3952-3957, vol. 67, No. 21, American Chemical Society.
Colby, Steven M., et al., Space-Velocity Correlation Focusing, Analytical Chemistry, Apr. 15, 1996, pp. 1419-1428, vol. 68, No. 8, American Chemical Society.
Cornish, Timothy J., et al., A Curved Field Reflectron Time-Of-Flight Mass Spectrometer For The Simultaneous Focusing Of Metastable Product Ions, Rapid Communication In Mass Spectrometry, 1994, pp. 781-785, John Wiley & Sons.
Cornish, Timothy J., et al., Tandem Time-Of-Flight Mass Spectrometer, Analytical Chemistry, Apr. 15, 1993, pp. 1043-1047, vol. 65, No. 8.
Hillenkamp, F., Laser Desorption Mass Spectrometry: Mechanisms, Techniques And Applications, 1989, pp. 354-362, vol. 11A, Heyden & Son, London.
Kaufmann, R., et al., Mass Spectrometric Sequencing Of Linear Peptides By Product-Ion Analysis In A Reflectron Time-Of-Flight Mass Spectrometer Using Matrix-Assisted Laser Desorption Ionization, Rapid Communications In Mass Spectrometry, 1993, pp. 902-910, vol. 7, John Wiley & Sons, Ltd.
Mamyrin, B.A., et al., The Mass-Reflectron, A New Nonmagnetic Time-Of-Flight Mass Spectrometer With High Resolution, Sov. Phys. 1973, pp. 45-48, Vo. 37, No. 1, American Institute of Physics.
Matsuda, H., et al., Particle Flight Times Through Electrostatic And Magnetic Sector Fields And Quadrupoles To Second Order, International Journal Of Mass Spectrometry And Ion Physics, 1982, pp. 157-168, vol. 42, Elsevier Scientific Publishing Company, Amsterdam, The Netherlands.
Neuser, H. J., et al., High-Resolution Laser Mass Spectrometry, International Journal Of Mass Spectrometry And Ion Process, 1984, pp. 147-156, vol. 60, Elsevier Science Publishers B.V., Amsterdam, The Netherlands.
Vestal, M. L., et al., Delayed Extraction Matrix-Assisted Laser Desorption Time-Of-Flight Mass Spectrometry, Rapid Communications In Mass Spectrometry, 1995, pp. 1044-1050, vol. 9, John Wiley & Sons, Ltd.
Vestal, M. L., et al., Resolution And Mass Accuracy In Matrix-Assisted Laser Desorption Ionization-Time-of-Flight, American Society For Mass Spectrometry, 1998, pp. 892-911, Elsevier Science Inc.
Vestal, M., High Performance MALDI-TOF Mass Spectrometry For Proteomics, International Journal Of Mass Spectrometry, 2007, pp. 83-92.
Wiley, W. C., et al., Time-Of-Flight Mass Spectrometer With Improved Resolution, The Review Of Scientific Instruments, Dec. 1955, pp. 1150-1157, vol. 26, No. 13.
Zhou, J., Kinetic Energy Measurements Of Molecular Ions Ejected Into An Electric Field By Matrix-Assisted Laser Desorption, Rapid Communications In Mass Spectrometry, Sep. 1992, pp. 671-678, vol. 6, John Wiley & Sons, Ltd.
Kim Robert
Rauschenbach Kurt
Rauschenbach Patent Law Group, LLP
Sahu Meenakshi S
Virgin Instruments Corporation
LandOfFree
Quantitative measurement of isotope ratios by time-of-flight... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Quantitative measurement of isotope ratios by time-of-flight..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Quantitative measurement of isotope ratios by time-of-flight... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2652211