Quantitative lateral flow assays and devices

Details Quantitative lateral flow assays and devices Quantitative lateral flow assays and devices

2006-11-08

2009-02-17

Chin, Christopher L (Department: 1641)

Chemistry: analytical and immunological testing

Involving diffusion or migration of antigen or antibody

C422S051000, C422S051000, C422S051000, C435S007920, C435S007940, C435S287200, C435S287700, C435S287900, C435S805000, C435S810000, C435S970000, C436S169000, C436S530000, C436S533000, C436S805000, C436S810000

Reexamination Certificate

active

07491551

ABSTRACT:
This invention provides solid phase specific binding lateral flow assay methods, devices and kits for quantitating high and low molecular weight analytes. The methods and devices of the invention employ labelled reagents which are either analyte analogs or complementary specific binding pair members for the analyte and a novel arrangement of capture zones comprising immobilized specific binding substances for either the analyte or the labelled reagent to effect bound from unbound labelled reagent as a function of analyte concentration. The capture zones are disposed on a non-bibulous matrix defining a flow path from a sample receiving zone to the capture zone. The devices of this invention also include multilane flow paths and multiple capture zones to quantitate analyte.

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