Quantitative evaluation of enteric microbial overgrowth

Details Quantitative evaluation of enteric microbial overgrowth Quantitative evaluation of enteric microbial overgrowth

1977-08-22

1979-10-16

Fagelson, Anna P.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

A61K 2900, G01N 3316

Patent

active

041713524

ABSTRACT:
A quantitative evaluation of the intestinal microflora is made by administering to an animal organism an effective amount of novel chemical conjugates of a bile acid or related acid with an amino acid which will be cleaved from the bile or related acid by the enzymes elaborated by the intestinal microflora and then measuring the amount of the released amino acid in the urine after a predetermined time interval. The novel compounds and their use in in vitro tests are included in the invention.

REFERENCES:
patent: 3745212 (1973-07-01), de Benneville
Lack et al, J. of Lipid Res., vol. 14, 1973 pp. 367-370.
Hill et al, Gut., vol. 9, 1968 pp. 22-27.
Wolgemuth, et al, Am. J. Dig. Dis., vol. 21, No. 9, Sep. 1976 pp. 821-826.
Wolgemuth et al Chem. Abs., vol. 85, 1976 Abs. No. 173791s.

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