Quantitative dosing of small amounts of liquids

Dispensing – Drop formers

Reexamination Certificate

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Details

C222S209000, C417S044200

Reexamination Certificate

active

07316336

ABSTRACT:
The invention relates to quantitative dosing of small amounts of liquids having a volume of microliter or nanoliter order. Such a dosing technique is useful for instance for productive serial dosing in applications of clinical chemistry. In dosing device of the invention, flexible bellows (5) attached to a body (1) define a liquid space (15) filled with a liquid to be dosed and communicate with a dosing tip (19). The bellows (5) are provided with an actuator (7) for operation thereof, constricting the liquid space to cause a liquid dose to be discharged from the dosing tip. The invention is further directed to a dosing method based on movements of bellows moved by a magnetic actuator, and to a method wherein liquid is dosed as individual small droplets from the dosing tip by first accelerating and then by slowing down the motion of the bellows by means of the actuator.

REFERENCES:
patent: 4154379 (1979-05-01), Schermutzki
patent: 4393982 (1983-07-01), Kuckens
patent: 5638986 (1997-06-01), Tuominen et al.
patent: 5641270 (1997-06-01), Sgourakes et al.
patent: 6623257 (2003-09-01), Taniguchi
patent: 925025 (1992-11-01), None
patent: 964029 (1996-10-01), None
patent: WO 94/11710 (1994-05-01), None
patent: WO 97/01081 (1997-01-01), None
patent: WO 98/15800 (1998-04-01), None

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