Quantitative analysis for diabetic condition predictor

Details Quantitative analysis for diabetic condition predictor Quantitative analysis for diabetic condition predictor

1992-09-30

1995-06-27

Scheiner, Toni R.

Chemistry: analytical and immunological testing

Oxygen containing

Hydroxyl containing

436536, 436173, 436811, 436815, 435 4, 435 71, 435 15, G01N 2400, G01N 3349, G01N 33493

Patent

active

054279569

ABSTRACT:
An enhanced quantitative assay for chiro-inositol concentration can be used to determine insulin-resistance, or a predisposition to the development of insulin-resistance, in type I and type II diabetics. Spot urine or serum samples reflecting concentrations of chiro-inositol below about 1.0 micrograms/ml in urine or 0.1 micrograms/ml in serum are indicative of a predisposition to the development of insulin-resistance, while concentrations below about 0.3 micrograms/ml or 0.03 micrograms/ml in serum are associated with actual insulin-resistance symptoms. The assay can be employed for patient diagnosis, insulin therapy monitoring, and family screening.

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