Quantitation of cancer procoagulant activity in serum

Details Quantitation of cancer procoagulant activity in serum Quantitation of cancer procoagulant activity in serum

1987-06-26

1988-11-15

Schor, Kenneth M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

435 13, 436 64, 436 69, 436177, 436813, 530412, C12Q 156, G01N 3348

Patent

active

047849401

ABSTRACT:
Methods and techniques are described for detecting the presence of cancer procoagulant activity in blood serum. The method provides a means of distinguishing persons or animals having cancer from those who do not have cancer. The method involves techniques for processing serum such that the activity of cancer procoagulant can be measured while the activity of other coagulation enzymes in the serum is minimized or eliminated. Then the serum can be analyzed for cancer procoagulant activity.

REFERENCES:
patent: 4447545 (1984-05-01), DeFazio
patent: 4461833 (1984-07-01), Gordon
patent: 4622389 (1986-11-01), Nagasawa
patent: 4678757 (1987-07-01), Rapkin
Gordon et al.; J. Natl. Cancer Inst., vol. 62, No. 4, Apr. 1979, pp. 773-776.
Gordon et al.; J. Clin. Invest., vol. 67, Jun. 1981, pp. 1665-1671.
Falanga et al.; Biochemistry, 24, 5558 (1985); pp. 5558-5567.

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