Quality control of assays

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

Reexamination Certificate

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C436S524000, C436S528000, C436S529000, C436S527000, C436S164000, C435S283100, C435S287100, C435S287200, C435S288300, C435S288700, C422S050000, C422S067000, C422S068100, C422S082050

Reexamination Certificate

active

10619735

ABSTRACT:
The invention relates to a device and methods for determining the quality of reagents used in an assay process, particularly a multistep immunohistochemical assay. In particular, the device comprises a substrate with a plurality of compounds affixed to a substrate, where each compound is reactive with a reagent used in the assay.

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Klebe, R..J., “Cytoscribing: a method for micropositioning cells and the construction of two- and three-dimensional synthetic tissues,”Exp. Cell Res.179:362-373 (1988).
Sompuram, S.R. et al., “A novel quality control slide for quantitative immunohistochemistry testing,”J. Histochem. Cytochem.50:1425-1434 (2002).
van der Ploeg, M. et al., “Matrix models. Essential tools for microscopic cytochemical research,”Histochemistry84:283-300 (1986).
Wittekind et al., “On the nature of Romanowsky-Giemsa staining and the Romanowsky-Giemsa effect. I. Model experiments on the specificity of azure B-eosin Y stain as compared with other thiazine dye-eosin Y combinations,”Histochem. J.17:263-289 (1985).

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