Quadroma cells and trioma cells and methods for the production o

Details Quadroma cells and trioma cells and methods for the production o Quadroma cells and trioma cells and methods for the production o

1984-06-18

1987-12-22

Moskowitz, Margaret

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435 68, 435 70, 4351722, 435948, 436548, 935 90, 935 92, 935 93, 935 95, 935100, 935104, 935107, 935108, 935110, C12N 500, C12N 1500, C07K 1504

Patent

active

047146818

ABSTRACT:
Antibodies having binding affinity for two desired antigens, hereinafter "recombinant monoclonal antibodies"; recombinant monoclonal antibodies produced by a quadroma cell or a trioma cell; and methods for producing recombinant monoclonal antibodies by means of a quadroma cell or a trioma cell, wherein a quadroma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a hybridoma cell which produces an antibody having specific binding affinity for another desired antigen, and wherein a trioma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a lymphocyte which produces an antibody having specific binding affinity to another desired antigen.

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