Pyruvate producing yeast strain

Details Pyruvate producing yeast strain Pyruvate producing yeast strain

2004-04-29

2008-07-29

Vogel, Nancy (Department: 1636)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Fungi

C435S255200

Reexamination Certificate

active

07405068

ABSTRACT:
Disclosed herein are glucose tolerant C2carbon source-independent (GCSI) yeast strains having no detectable amount of pyruvate decarboxylase activity, wherein wild type yeast strains for the glucose tolerant C2carbon source-independent yeast strains are Crabtree positive. Also disclosed are methods of selecting glucose tolerant C2carbon source-dependent yeast strains, and methods of producing pyruvic acid or salts thereof using glucose tolerant C2carbon source-independent yeast strain. Further disclosed herein are GCSI yeast strains having a genome that comprises an exogenous lactate dehydrogenase gene.

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