Pyruvate carboxylase from Corynebacterium glutamicum

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

Reexamination Certificate

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C435S183000

Reexamination Certificate

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06884606

ABSTRACT:
The present invention concerns an anaplerotic enzyme fromCorynebacterium glutamicumwhich replenishes oxaloacetate consumed during lysine and glutamic acid production in industrial fermentations. In particular, isolated nucleic acid molecules are provided encoding the pyruvate carboxylase protein. Pyruvate carboxylase polypeptides are also provided.

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