Pyrrolotriazolopyrimidinone derivatives

Details Pyrrolotriazolopyrimidinone derivatives Pyrrolotriazolopyrimidinone derivatives

2006-06-13

2006-06-13

McKenzie, Thomas C. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C544S280000, C514S267000

Reexamination Certificate

active

07060824

ABSTRACT:
This invention relates to new therapeutically useful 8-(disubstituted)phenyl-6,9-dihydro-5H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-c]pyrimidine-5-one and 8-phenyl-6,9-dihydro-5H-pyrrolo[3,2-e][1,2,4]triazolo[4,3-c]pyrimidine-5-one derivatives of formula (I): wherein: —X—C—Y— represents (a) or (b) to processes and intermediates for their preparation, to pharmaceutical compositions containing them and to their medical uses as potent and selective inhibitors of phosphodiesterase 5 (PDE 5).

REFERENCES:
patent: WO 99/62905 (1999-12-01), None

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