Pyrrolotriazolopyrimidine derivatives and process for the prepar

Details Pyrrolotriazolopyrimidine derivatives and process for the prepar Pyrrolotriazolopyrimidine derivatives and process for the prepar

1976-05-04

1977-02-08

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424251, C07D48714

Patent

active

040071898

ABSTRACT:
Pyrrolotriazolopyrimidine derivatives having the formula ##STR1## wherein R.sup.1 represents hydrogen atom or an alkyl group having from 1 to 4 carbon atoms and R.sup.2 represents an alkyl group having from 1 to 4 carbon atoms, a cycloalkyl group having from 5 to 8 carbon atoms, a phenyl group optionally substituted with one or more halogen atoms or a phenylalkyl group having the formula ##STR2## IN WHICH R.sup.3 represents hydrogen atom or an alkyl group having from 1 to 4 carbon atoms, R.sup.4 represents halogen atom, an alkyl group having from 1 to 4 carbon atoms or an alkoxy group having from 1 to 4 carbon atoms, m represents an integer from 0 to 2 and n represents an integer from 0 to 3, and pharmacologically acceptable salts thereof. The compounds are useful as vasodilating or hypotensive agents and may be prepared by reacting triazolopyrimidine derivatives having the formula ##STR3## wherein X.sup.1 and X.sup.2 may be the same or different and each represents a halogen atom and R.sup.1 has the same meaning as defined above with an amine having the formula

REFERENCES:
patent: 3769288 (1973-10-01), Stahale et al.
patent: 3868374 (1975-02-01), Yale et al.

Affiliated with

Also associated with

Rating

Pyrrolotriazolopyrimidine derivatives and process for the prepar does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pyrrolotriazolopyrimidine derivatives and process for the prepar, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrrolotriazolopyrimidine derivatives and process for the prepar will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1212877