Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-04-01
2000-08-01
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514267, 544250, 544280, A61K 31505, C07D48704
Patent
active
060967498
ABSTRACT:
The invention relates to the use of the compounds mentioned below in the therapeutic treatment of tumor diseases and other proliferative diseases, such as psoriasis, and to novel compounds of that type. The compounds are compounds of formula I ##STR1## wherein n is from 0 to 5 and, when n is not 0,
REFERENCES:
patent: 3037980 (1962-06-01), Hitchings et al.
patent: 3311628 (1967-03-01), Partyka
patent: 3631045 (1971-12-01), Kim et al.
patent: 4229453 (1980-10-01), Roth et al.
patent: 5034393 (1991-07-01), Hackler et al.
patent: 5256650 (1993-10-01), Peet et al.
patent: 5350749 (1994-09-01), Hackler et al.
patent: 5496822 (1996-03-01), Akimoto et al.
patent: 5519018 (1996-05-01), Matusch et al.
patent: 5543413 (1996-08-01), Townsend et al.
patent: 5654307 (1997-08-01), Bridges et al.
patent: 5674998 (1997-10-01), Boyer et al.
patent: 5869485 (1999-02-01), Missbach
Burke, "Protein-Tyrosine Kinases: Potential Targets for Anticancer Drug Development," STEM CELLS, vol. 12, pp. 1-6, 1994.
Traxler et al., "4-(Phenylamino)pyrrolopyrimidines: Potent and Selective, ATP Site Directed Inhibitors of the EGF-Receptor Protein Tyrosine Kinase," J. Med. Chem., vol. 39, pp. 2285-2292, Jul. 1996.
Jacobi et al., "Antiinflammatory intermediate 7H-pyrrolo-[2,3-d]-pyrimidine derivatives," Derwent Abstract, from DE 3036390, May 13, 1982.
Jorgensen, et al. Chemica Scripta, 28 (4) 427-429 (1988).
Jorgensen, et al., Chemica Scripta, 28 (2) 201-204 (1988).
West, et al., J. Org. Chem., 26, 3809-3812 (1961).
Iwamura, et al. J. Med. Chem. 26, (6) 838-844, (1983).
Iwamura, et al. J. Pesticide Science, 6, (1), 9-15, (1981).
Iwamura, et al., Phytochemistry, 18, (2) 217-222 (1979).
Jorgensen, et al., J. Heterocyclic Chem., 22:859 (1985).
Girgis, et al., Liebigs Ann. Chem. 2066-2072 (1983).
Jorgensen, et al., Liebigs Ann. Chem: 142:148 (1985).
Girgis, et al., Synthesis (1): 101-104 (1985).
Jorgenson, et al., Chem. Scripta 25, 222-226 (1985).
Brill Wolfgang K.-D.
Furet Pascal
Traxler Peter
Novartis Corporation
Raymond Richard L.
Wildman David E.
LandOfFree
Pyrrolopyrimidine derivatives having pharmacological activity does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pyrrolopyrimidine derivatives having pharmacological activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrrolopyrimidine derivatives having pharmacological activity will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-664221