Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
2007-09-18
2007-09-18
Berch, Mark L. (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
C544S244000
Reexamination Certificate
active
10732509
ABSTRACT:
The invention relates to compounds of the formula 1or a pharmaceutically acceptable salt, prodrug or hydrates thereof, wherein Q, A, L, R1, R2and R3are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula 1.
REFERENCES:
patent: 6001839 (1999-12-01), Calderwood
patent: 6051577 (2000-04-01), Altmann
patent: 2003/0207870 (2003-11-01), Dumas et al.
patent: 3145287 (1983-05-01), None
patent: 981458 (1965-01-01), None
patent: 9732879 (1997-09-01), None
patent: 0017202 (2000-03-01), None
patent: 0017203 (2000-03-01), None
patent: 0172751 (2000-03-01), None
patent: 0200651 (2002-01-01), None
West, Anthony R., Solid State Chemistry and its Applications, Wiley, New York, 1988, pp. 358 & 365.
Wolff, Manfred E. “Burger's Medicinal Chemistry, 5ed, Part I”, John Wiley & Sons, 1995, pp. 975-977.
Banker, G.S. et al, “Modern Pharmaceutics, 3ed.”, Marcel Dekker, New York, 1996, pp. 451 and 596.
Burchat, A. F.; Calderwood, D. J.; Hirst, G. C.; Holman, N. J.; Johnston, D. N.; Munschauer, R.; Rafferty, P.; Tometzki, G. B., Bioorganic & Medicinal Chemistry Letters, 10(19), 2171-2174 (English) 2000.
Newman et. al. (DDT; 2003; 8(19); 898-905).
Renau T. E. et al., Journal of Medicinal Chemistry, vol. 39, No. 4, pp. 873-880 (1996).
Abdelhamid A. O. et al., Heterocycles, vol. 27, No. 8, pp. 1861-1866 (1988).
Steinhilber D. et al., Pharmaceutical Research, vol. 3, No. 5, pp. 271-277 (1986).
Folkers G. et al., Journal of Molecular Graphics, vol. 3, No. 4, pp. 146-150 (1985).
Mueller, C. E. et al., Journal of Medicinal Chemistry, vol. 33(10), pp. 2822-2828 (1990).
Renau, T. E. et al., Bioorganic & Medicinal Chemistry Letters, vol. 2, No. 12, pp. 1755-1760 (1992).
Taylor E. C. et al., Journal of the American Chemical Society, vol. 87(9), pp. 1995-2003 (1965); and.
Daly J. W. et al., Biochemical Pharmacology, vol. 37, No. 19, pp. 3749-3753 (1988).
Arcari Joel T.
Chen Jinshan
La Greca Susan D.
Marx Matthew A.
Wessel Matthew D.
Berch Mark L.
Kim Sandra
Moore Susanna
Pfizer Inc
Zelson Steve T.
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