Pyrrolopyrazolopyrimidine compound and medicine comprising the s

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544251, A01N 4354, A61K 31505, C07D23900

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active

060573309

ABSTRACT:
The invention relates to compounds represented by the following general formula (1): ##STR1## wherein R.sup.1 represents an alkyl group, R.sup.2 represents an amino group, alkyl group or the like, and R.sup.3 represents a nitro group, amino group, heterocyclic group, alkylsulfonylamino group or the like, or salts thereof, medicines comprising such a compound, a preparation process of the compounds, and intermediates useful for preparation thereof. The compounds (1) are useful for the prevention and treatment of a respiratory disease.

REFERENCES:
patent: 4992442 (1991-02-01), Tsujitani et al.
patent: 5086057 (1992-02-01), Sasagawa
Naoki Hiyama et al., "Effect of Novel Bronchiadilator Drug PR-001337 on Bronchial Smooth Muscle of Guinea Pig," Journal of Smooth Muscle Research, Japanese Section, vol. 1, No. 2, (Jul. 1997), 4 pages. (English translation 2 pages).

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