Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-06-27
2006-06-27
Coleman, Brenda (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C540S496000
Reexamination Certificate
active
07067511
ABSTRACT:
Compounds of the formulae Ia and Ib:wherein:A is CH2, or a single bond;R2is selected from: R, OH, OR, CO2H, CO2R, COH, COR, SO2R, CN;R6, R7and R9are independently selected from H, R, OH, OR, halo, amino, NHR, nitro, Me3Sn;and R8is selected from H, R, OH, OR, halo, amino, NHR, nitro, Me3Sn, where R is as defined above, or the compound is a dimer with each monomer being the same or different and being of formula Ia or Ib, where the R8groups of the monomers form together a bridge having the formula —X—R′—X— linking the monomers, where R′ is an alkylene chain containing from 3 to 12 carbon atoms, which chain may be interrupted by one or more hetero-atoms and/or aromatic rings and may contain one or more carbon-carbon double or triple bonds, and each X is independently selected from O, S, or N;except that in a compound of formula Ia when A is a single bond, then R2is not CH═CH(CONH2) or CH═CH(CONMe2). Other related compounds are also disclosed.
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Howard Philip Wilson
Thurston David Edwin
Coleman Brenda
Frenchick Grady J.
Michael & Best & Friedrich LLP
Spirogen Limited
Yager Charlene L.
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