Pyrrolo benzodiazepine compounds

Details Pyrrolo benzodiazepine compounds Pyrrolo benzodiazepine compounds

1978-10-02

1980-01-22

Rotman, Alan L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424274, 2602393P, C07D48704

Patent

active

041850165

ABSTRACT:
Novel perhydro-1H-pyrrolo[2,1-C][1,4]benzodiazepin-5-one compounds having antitumor activity, perhydro-1H-pyrrolo[2,1-C][1,4]-benzodiazepin-5,11-dione compounds which are synthetic intermediate of the former, and processes for producing these compounds.

REFERENCES:
patent: 3523941 (1970-08-01), Leimgruber et al.
patent: 3524849 (1970-08-01), Batcho et al.
patent: 3947408 (1976-03-01), Wright
patent: 3985732 (1976-10-01), Wright
Kameda et al., "Chem. Pharm. Bull." vol. 16, No. 3, pp. 480-485 (1968).
Chemical Abstracts, vol. 87, (1977) item 135268k, abstracting Scalzo et al., in "Farmaco Ed. Sci.", (1977), (Aug.), vol. 32, No. 5, pp. 579-591.

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