Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
2000-02-17
2000-10-24
Ford, John M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
C07D48704
Patent
active
061369748
ABSTRACT:
The invention provides certain novel 5-substituted pyrrolo[3,4-d]pyrimidine-2,4-diones, processes for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and methods of treatment involving their use.
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Noguchi et al, "A Facile Preparation of 7-(Substituted amino)-6H-pyrrolo[3,4-d]-pyrimidine Derivatives.sup.1 ," Bull. chem. Soc. Jpn., vol. 62, pp. 3043-3045 (1989).
Hirota et al, "Pyrimidine Derivatives and Related Compounds. XXXIII..sup.1) Reactions of . . . , " Chem. Pharm. bull., Vol. 29, No. 6, pp. 1525-1532 (1981).
Senda et al, "A Facile Synthesis of Pyrrolo[3, 4-d]pyrimidines and Pyrimido[4,5-d]pyridazines," communications, "Synthesis, " pp. 463-465 (1978).
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Cheshire David R
Cooper Martin E
Donald David K
Furber Mark
Harrison Richard P
AstraZeneca UK Limited
Ford John M.
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