Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
2000-02-17
2000-12-26
Ford, John M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
C07D48704
Patent
active
061662062
ABSTRACT:
The invention provides certain novel 5-substituted pyrrolo[3,4-d]pyrimidine-2,4-diones, processes for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and methods of treatment involving their use.
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Noguchi et al, "A Facile Preparation of 7-(Substituted amino)-6H-pyrrolo[3,4-d]-pyrimidine Derivatives.sup.1," Bull. Chem. Soc. Jpn., vol. 62, pp. 3043-3045 (1989).
Hirota et al, "Pyrimidine Derivatives and Related Compounds. XXXIII. .sup.1) Reactions of . . . ," Chem. Pharm. Bull., vol. 29, No. 6, pp. 1525-1532 (1981).
Senda et al, "A Facile Synthesis of Pyrrolo[3,4-d]pyrimidines and Pyrimido[4,5-d]pyridazines," Communications, "Synthesis," pp. 463-465 (1978).
Baines et al, "Functional Characterization of Novel lL-2 Transcriptional Inhibitors," The Journal of Immunology, vol. 154, pp. 3667-3677 (1995).
Cheshire David R
Cooper Martin E
Donald David K
Furber Mark
Harrison Richard P
AstraZeneca UK Limited
Ford John M.
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