Pyrrolo [3,4-c]quinoline compounds

Details Pyrrolo [3,4-c]quinoline compounds Pyrrolo [3,4-c]quinoline compounds

1981-01-08

1982-09-21

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 65, 424258, C07D49114, C07D49122

Patent

active

043508146

ABSTRACT:
Pyrrolo [3,4-c]quinolines are described which have various substitutions at the 2, 4, 5, 6, 7, 8 and 9 positions. The group of compounds has been found to possess unexpected pharmaceutical utilities including antipsychotic, analgesic and antidepressant activities. Also set forth are various methods of making the compounds as well as pharmaceutical compositions containing them.

REFERENCES:
patent: 3024243 (1962-03-01), Sang et al.
H. Fritz et al., "Cyclisierung von Phenylhydrazonen . . . ," Liebigs Ann. Chem., 762, 121-126, (1972).
J. M. Fayadh et al., "The Chemical Effects of .gamma.-Radiation . . . " J. Chem. Soc., 1781-1784, (1969).
H. Fritz et al., "Eine neue Synthese fur 2H-Pyrrolo . . . ," Liebigs Ann. Chem., 255-265, (1975).
R. B. Roy et al., "Studies on the Reaction of Benzoyl Peroxide . . . ", J. Chem. Soc., 1886-1891, (1969).

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