Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-08-07
2000-01-04
Huang, Evelyn Mei
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 84, A61K 3147, C07D47104
Patent
active
060110449
ABSTRACT:
The present invention relates to a novel pyrrolo[3,2-c]quinoline derivatives containing haloalkoxy group, represented by Formula I, their pharmaceutically acceptable salts; process for preparation thereof; and pharmaceutical composition thereof for treating gastric ulcer. ##STR1## in which R.sub.1 is haloalkoxy group of C.sub.1 -C.sub.6 including trifluoromethoxy, difluoromethoxy and trifluoroethoxy group.
REFERENCES:
patent: 5051508 (1991-09-01), Brown
Leach et al., "Reversible Inhibitors of the Gastric (H.sup.+ /K.sup.+) -ATPase. 2.1-Arylpyrrolo [.[.3, 2-c] quinolines: Effect of the 4-Substituent ", J. Med.Chem. 1992, 35, 1845-1852.
Cheon Hyae-Gyeong
Choi Joong-Kwon
Kang Seung-Kyu
Kim Hyo-Jung
Kim Sung-soo
Huang Evelyn Mei
Korea Research Institute of Chemical Technology
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