Pyrrolo [3,2,1-ij]-quinoline carboxylic acid compound

Details Pyrrolo [3,2,1-ij]-quinoline carboxylic acid compound Pyrrolo [3,2,1-ij]-quinoline carboxylic acid compound

1984-01-24

1986-06-10

Lesmes, George F.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544361, 544372, C07D40304, C07D40104, A61K 31495

Patent

active

045943478

ABSTRACT:
Benzo-heterocyclic compounds of the formula: ##STR1## wherein R.sup.1 is a lower alkyl group; R.sup.2 is a halogen atom or a group of the formula ##STR2## (wherein R.sup.4 and R.sup.5 combine together with the nitrogen atom to which they bind to form a 5- or 6-membered saturated heterocyclic group which may optionally contain an oxygen atom or nitrogen atom within the ring as an additional hetero atom and may also optionally have a substituent selected from a lower alkyl or hydroxy group on the hetero ring); R.sup.3 is an amino or nitro group; X is a halogen atom; and n is an integer of 1 or 2, and a salt thereof, which have excellent antimicrobial activities and are useful as an antimicrobial agent, or as an intermediate for the preparation of an active compound.

REFERENCES:
patent: 3917609 (1975-11-01), Gerster
patent: 4399134 (1983-11-01), Ishikawa et al.
patent: 4416884 (1983-11-01), Ishikawa et al.

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