Pyrrolo[2,3-d]Pyrimidines as Protein Tyrosine Kinase Inhibitors

Details Pyrrolo[2,3-d]Pyrimidines as Protein Tyrosine Kinase Inhibitors Pyrrolo[2,3-d]Pyrimidines as Protein Tyrosine Kinase Inhibitors

2005-02-17

2009-12-01

Wilson, James O (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S280000, C544S118000, C514S265100

Reexamination Certificate

active

07625894

ABSTRACT:
The invention relates to 7H-pyrrolo[2,3-d]-pyrimidine derivatives of formula (I), wherein the symbols and substituents are as defined in the description, to processes for the preparation thereof to pharmaceutical compositions comprising such derivatives and to the use of such derivatives—alone or in combination with one or more other pharmaceutically active compounds —for the preparation of pharmaceutical compositions for the treatment especially of a proliferative disease, such as a tumor.

REFERENCES:
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Caravatti, G. et al., “Pyrroloa2, 3-Upyrimidine and Pyrazoloa3, 4-Dupyrimidine Derivatives as Selective Inhibitors of the EGF Receptor Tyrosine Kinase”, ACS Symposium Series, 2001 vol. 796 pp. 231-244.

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