Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-12-27
2005-12-27
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C540S496000
Reexamination Certificate
active
06979684
ABSTRACT:
The present invention relates to novel pyrrolo[2,1-c][1,4]benzodiazepine-napthalimide hybrids linked through piperazine moiety as potential antitumour agents. The present invention also relates to a process for the preparation of novel pyrrolo[2,1-c][1,4]benzodiazepine-napthalimide hybrids linked through piperazine moiety useful as potential antitumour agents.
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patent: 94/07862 (1994-04-01), None
patent: 01/66545 (2001-09-01), None
Kamal, A., et al. “Design and Synthesis of C-8 Linked Pyrrolobenzodiazepine-Naphthalimide Hybrids as Anti-Tumour Agents.”Bioorganic&Medicinal Chemistry Letters(2002) vol. 12, No. 15, pp 1933-1935 XP-002316525.
Kamal, A., et al.“Recent Developments inthe Design, Synthesis and Structure-Activity Relationship Studies of Pyrrolo [2,1-c][1,4] benzodiazepines as DNA-Interactive Antitumour Antibiotics.”Current Medicinal Chemistry-Anti-Cancer Agents(2002) vol. 2, No. 2, pp 215-254.
Kamal, A., et al. “Synthesis of C-8 Alkylamino Substituted Pyrrolo[2,1-c][1,4]-benzodiazepines as Potential Anti-Cancer Agents.”Bioorganic&Medicinal Chemistry Letters(2002) vol. 12, No. 15, pp 1917-1919 XP-002316526.
Kamal Ahmed
Khanna Gollpalli Bhasker Ramesh
Rondla Ramu
Council of Scientific and Industrial Research
Kifle Bruck
Ladas and Parry LLP
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