Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-06-01
2000-06-27
Chang, Ceila
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 94, A61K 3144, C07D47112
Patent
active
060807547
ABSTRACT:
The present invention relates to therapeutically active compounds of formula I ##STR1## a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the prevention or treatment of estrogen related diseases or syndromes.
REFERENCES:
patent: 2986563 (1961-05-01), Boekelheide et al.
Tsuchiya et al. "thermal intramolecular cyclization of 2-ethynylpyridine N-ylides to indolizines and cyclazines" Chem. Phar. bull. v.32(11) 4666-4669, 1985.
Pohjala "Indolizine Derivatives IX . . . " J. Het. Chem. vol. 15(6) 955-960, 1978.
Sashida et al. "Thermal reaarangement of cyclic amine ylides . . . " CA 110:231395, 1988.
Bury Paul Stanley
Christiansen Lise Brown
Jacobsen Poul
Jorgensen Anker Steen
Kanstrup Anders
Chang Ceila
Novo Nordisk A S
Rozek Carol E.
Zelson Steve T.
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